Thionyl Chloride → HCID 12366432, compound

HRID 596901Notes

Reaction equation

HRID 596901 reaction equation
[C:1]([O:4][C:5]1[CH:13]=[C:12]([CH3:14])[C:11]([CH2:15][CH3:16])=[CH:10][C:6]=1[C:7](O)=[O:8])(=[O:3])[CH3:2].S(Cl)([Cl:19])=O>C1C=CC=CC=1>[C:1]([O:4][C:5]1[CH:13]=[C:12]([CH3:14])[C:11]([CH2:15][CH3:16])=[CH:10][C:6]=1[C:7]([Cl:19])=[O:8])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 123664232-(Acetyloxy)-5-ethyl-4-methylbenzoic acid

Product 1

HCID 12366432HCID 12366432, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of 2-acetoxy-5-ethyl-4-methylbenzoic acid (11.10 g) and thionyl chloride (20 ml) in dry benzene (100 ml) was heated under reflux for 6 hours, cooled and solvents removed in vacuo. The crude 2-acetoxy-5-ethyl-4-methylbenzoyl chloride was obtained as a liquid which was used as rapidly as possible in the next stage of the synthesis without further purification.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for 6 hours
  3. temperaturecooled
  4. customsolvents removed in vacuo

Sources & evidence

ORD record
ord-d2a4892efc7a4cf9a07371eed6c9562e
Source dataset
uspto-grants-1977_03
Patent number
US04012407

Reaction notes

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