HCID 12369008, compound → HCID 12369024, compound

Participants

Reaction Steps

The benzyl alcohol (0.7 g., 1.5 mmol) in 150 ml. of ethanol is hydrogenated over 0.7 g. of 10% palladium-on-carbon at 50 psi for 25 minutes. The catalyst is filtered and the filtrate evaporated to give α-(t-butylaminomethyl)-4-hydroxy-3-(2-hydroxy-1-methoxyethyl)-benzyl alcohol; fumarate m.p. 230° C. (decomp.).

Provenance & Evidence