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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 597023Generated: October 25, 2026

Formaldehyde → 2',3'-Dichloro-4'-methylthio-2-cyclopentylacrylophenone

https://huagongshe.com/reaction/597023

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantSulfuric AcidHCID 1118—
Reactant2',3'-Dichloro-4'-methylthio-2-cyclopentylacetophenoneHCID 20358446—
Solvent1,4-DioxaneHCID 31275—
Product2',3'-Dichloro-4'-methylthio-2-cyclopentylacrylophenoneHCID 20358460—

Reaction Steps

2',3'-dichloro-4'-methylthio-2-cyclopentylacrylophenone is prepared following substantially the same procedure described in Example 3, Step B, using the following substances: 2',3'-dichloro-4'-methylthio-2-cyclopentylacetophenone (54.5 g., 0.18 mole), paraformaldehyde (21.6 g., 0.72 mole), concentrated sulfuric acid (9.65 g.) and dioxane (450 ml.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04012524
Source datasetuspto-grants-1977_03
ORD IDord-8b9de3dec3c8441a867aa0d9fc4dc098
Source noteuspto-grants-1977_03