Methyl iodide → 2-Cyclopentyl-2-methyl-5-methylthio-6,7-dichloro-1-indanone

HRID 597025Notes

Reaction equation

HRID 597025 reaction equation
[CH:1]1([CH:6]2[CH2:14][C:13]3[C:8](=[C:9]([Cl:18])[C:10]([Cl:17])=[C:11]([S:15][CH3:16])[CH:12]=3)[C:7]2=[O:19])[CH2:5][CH2:4][CH2:3][CH2:2]1.[H-].[Na+].[CH3:22]I>COCCOC>[CH:1]1([C:6]2([CH3:22])[CH2:14][C:13]3[C:8](=[C:9]([Cl:18])[C:10]([Cl:17])=[C:11]([S:15][CH3:16])[CH:12]=3)[C:7]2=[O:19])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 24758Sodium hydrideHCID 203584542-Cyclopentyl-5-methylthio-6,7-dichloro-1-indanone

Product 1

HCID 203584612-Cyclopentyl-2-methyl-5-methylthio-6,7-dichloro-1-indanone

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

2-Cyclopentyl-2-methyl-5-methylthio-6,7-dichloro-1-indanone is prepared following substantially the same procedure described in Example 5, Step A, using the following substances: 2-cyclopentyl-5-methylthio-6,7-dichloro-1-indanone (7.9 g., 0.025 mole), 1,2-dimethoxyethane (200 ml.), sodium hydride (660 mg., 0.0275 mole) and methyl iodide (7.5 ml.).

Sources & evidence

ORD record
ord-538821035fda4bd0a64f66dee791bc39
Source dataset
uspto-grants-1977_03
Patent number
US04012524

Reaction notes

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