HCID 54411900, compound → HCID 12395569, compound

HRID 597029Notes

Reaction equation

HRID 597029 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[C:6]([C:9](=[O:20])[C:10](=[CH:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:11][CH3:12])[CH:5]=[CH:4][C:3]=1[O:21][CH3:22]>O>[CH2:11]([CH:10]1[CH:13]([C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)[C:5]2[C:6](=[C:7]([Cl:8])[C:2]([Cl:1])=[C:3]([O:21][CH3:22])[CH:4]=2)[C:9]1=[O:20])[CH3:12]

Participants

3

Reactant 1

HCID 54411900HCID 54411900, compound

Product 1

HCID 12395569HCID 12395569, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A stirred mixture of 2,3-dichloro-4-(2-benzylidenebutyryl)anisole (55.6 g., 0.166 mole) and polyphosphoric acid (550 g.) is heated at 95°-100° C. for 6 hours than at 80°-85° C. for 16 hours, and then poured into water (2 l.) affording 2-ethyl-3-phenyl-5-methoxy-6,7-dichloro-1-indanone which melts at 114°-116° C. after recrystallization from acetic acid-water.

Workup

  1. temperatureis heated at 95°-100° C. for 6 hours than at 80°-85° C. for 16 hours

Sources & evidence

ORD record
ord-85cc6011884b44aab1ddead68ca47636
Source dataset
uspto-grants-1977_03
Patent number
US04012524

Reaction notes

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