HCID 54411900, compound → HCID 12395569, compound

Participants

Reaction Steps

A stirred mixture of 2,3-dichloro-4-(2-benzylidenebutyryl)anisole (55.6 g., 0.166 mole) and polyphosphoric acid (550 g.) is heated at 95°-100° C. for 6 hours than at 80°-85° C. for 16 hours, and then poured into water (2 l.) affording 2-ethyl-3-phenyl-5-methoxy-6,7-dichloro-1-indanone which melts at 114°-116° C. after recrystallization from acetic acid-water.

Provenance & Evidence