Hydrochloric Acid → HCID 21449358, compound

Participants

Reaction Steps

A mixture of N-phenyl-N-(2,6-dichloropyrimidin-4-yl)hydrazine (30g.) and laevulinic acid (50g.) was heated at 100° C. for 3 hours whilst a stream of hydrogen chloride gas was passed through it. The mixture was cooled and added to water (400ml.), and the resulting mixture filtered to give 1-(2,6-dichloropyrimidin-4-yl)-2-methylindol-3-ylacetic acid, m.p. 205°-207° C.

Provenance & Evidence