Phenylhydrazine → HCID 21449354, compound

HRID 597038Notes

Reaction equation

HRID 597038 reaction equation
[Cl:1][C:2]1[N:7]=[C:6](Cl)[CH:5]=[C:4]([Cl:9])[N:3]=1.[C:10]1([NH:16][NH2:17])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.O.O.O.C([O-])(=O)C.[Na+]>O.C(O)C>[C:10]1([N:16]([C:6]2[CH:5]=[C:4]([Cl:9])[N:3]=[C:2]([Cl:1])[N:7]=2)[NH2:17])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

6

Reactant 3

HCID 7516PhenylhydrazineHCID 773782,4,6-TrichloropyrimidineHCID 23665404Sodium Acetate Trihydrate

Product 1

HCID 21449354HCID 21449354, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

A mixture of 2,4,6-trichloropyrimidine (50ml.) and phenylhydrazine (45ml.) was added to a solution of sodium acetate trihydrate (100g.) in water (270ml.) and ethanol (720ml.). The resulting mixture was kept at room temperature for 3 days. The resulting crystalline precipitate was collected by filtration, washed with ethanol (100ml.) and dried at 60° C. to give N-phenyl-N-(2,6-dichloropyrimidin-4-yl)hydrazine, m.p. 114°-116° C.

Workup

  1. filtrationThe resulting crystalline precipitate was collected by filtration
  2. washwashed with ethanol (100ml.)
  3. customdried at 60° C.

Sources & evidence

ORD record
ord-f23c618bd59a4c60af6443733b347853
Source dataset
uspto-grants-1977_03
Patent number
US04012513

Reaction notes

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