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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 597046Generated: October 31, 2026

Sodium Hydroxide → HCID 131710682, compound

https://huagongshe.com/reaction/597046

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 131710684HCID 131710684—
SolventEthanolHCID 702—
ProductHCID 131710682HCID 131710682—

Reaction Steps

Ethyl 5-methoxy-2-methyl-1-(2-phenylquinol-4-yl)indol-3-ylacetate (2.1g.) in ethanol (20ml.) and 2N-sodium hydroxide solution (20ml.) was refluxed for 0.25 hour. Most of the ethanol was removed in vacuo and the residue was diluted with water (50ml.). The resulting mixture was filtered, and the residue was washed with water and dried at 60° C. to give 5-methoxy-2-methyl-1-(2-phenylquinol-4-yl)indol-3-ylacetic acid sodium salt monohydrate, m.p. 179°-180° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04012513
Source datasetuspto-grants-1977_03
ORD IDord-d33a04eee10542f4b31e75fb71dbb77a
Source noteuspto-grants-1977_03