HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indoline → Methyl 5-dimethylamino-2-methyl-1-quinazolin-4-ylindolin-3-ylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indoline | HCID 10328 | — |
| Reactant | 4-Chloroquinazoline | HCID 78864 | — |
| Reactant | Ethyl 1-quinazolin-4-ylindolin-3-ylacetate | HCID 54457736 | — |
| Product | Methyl 5-dimethylamino-2-methyl-1-quinazolin-4-ylindolin-3-ylacetate | HCID 54450388 | — |
Reaction Steps
This indoline derivative was then reacted with 4-chloroquinazoline in a similar manner to that described in Example 4 for the preparation of ethyl 1-quinazolin-4-ylindolin-3-ylacetate, and there was obtained methyl 5-dimethylamino-2-methyl-1-quinazolin-4-ylindolin-3-ylacetate, as a syrup which was shown to be pure by TLC (systems A and B).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04012513 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-e1b8d66455274e0fa7ae452a9f1b90f5 |
| Source note | uspto-grants-1977_03 |