Methylamine → HCID 86734557, compound

Participants

Reaction Steps

Methyl 1-(7-chloroquinol-4-yl)-5-methoxy-2-methylindol-3-ylacetate (1.7g.) in methanol (50ml.) containing 30% w/v methylamine solution (25ml.) was refluxed for 10 hours. The solvents were evaporated in vacuo and the residue crystallised from a 1:1 v/v mixture of benzene and cyclohexane to give 1-(7-chloroquinol-4-yl)-5-methoxy-N,2-dimethylindol-3-ylacetamide, m.p. 168°-169° C.

Provenance & Evidence