Propylamine → HCID 21446379, compound

Participants

Reaction Steps

3.59 g (0.01 mole) of the 1-(3,5-bis-trifluoromethylphenyl)-2-oxo-pyrrolidine-4-carboxylic acid chloride, produced according to Example 4, paragraph 1, is dissolved in 400 ml of benzene, and 1.2 g (0.02 mole) of N-n-propylamine is added to the solution. After subsequent processing as described in Example 4 there is obtained 3.1 g (81% of theory) of 1-(3,5-bis-trifluoromethylphenyl)-2-oxo-pyrrolidine-4-carboxylic acid-N-n-propylamide; m.p. 152.5° - 154° C. Analysis for C16H16F6N2O2 (molar weight 382.32):

Provenance & Evidence