Hydrochloric Acid → 2,2-Dibromo-3,3-dimethylbutyric acid

HRID 597147Notes

Reaction equation

[Br:1][C:2]([Br:10])([C:6]([CH3:9])([CH3:8])[CH3:7])[C:3]([O-:5])=[O:4].[NH+]1C=CC=CC=1.Cl>>[Br:1][C:2]([Br:10])([C:6]([CH3:9])([CH3:8])[CH3:7])[C:3]([OH:5])=[O:4]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 21446895HCID 21446895, compound

Product 1

HCID 214468942,2-Dibromo-3,3-dimethylbutyric acid

Procedure

A mixture of 10 parts of pyridinium 2,2-dibromo-3,3-dimethylbutyrate and 50 parts of 50% aqueous hydrochloric acid resulted in precipitation of 2,2-dibromo-3,3-dimethylbutyric acid in quantitative yield. The solid was recrystallized from butyl chloride, m.p. 241° - 243° C. It can then be reacted with thiocarbohydrazide as described in Example 1 to form 4-amino-6-t-butyl-3-mercapto-1,2,4-triazin-5-one.

Sources & evidence

ORD record: ord-61a06702f8a84db6a5bec18c81ae1099
Source dataset: uspto-grants-1977_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04013649

Reaction notes

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