2-Chlorobenzoyl chloride → HCID 22749031, compound

HRID 597220Notes

Reaction equation

HRID 597220 reaction equation
[Cl-:1].[NH2:2][N+:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[Cl:9][C:10]1[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=1[C:12](Cl)=[O:13]>C1(C)C(C)=CC=CC=1>[Cl-:9].[Cl:1][C:17]1[CH:16]=[CH:15][C:11]([C:12]([NH:2][N+:3]2[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=2)=[O:13])=[CH:10][CH:18]=1

Participants

4

Reactant 2

HCID 691102-Chlorobenzoyl chlorideHCID 12210597N-amino-pyridinium chloride

Product 1

HCID 22749031HCID 22749031, compoundYield 97%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

1-Aminopyridinium chloride (104 parts) and -chlorobenzoyl chloride (150 parts) were heated in xylene (750 parts) at 140° C for 4 hours. The solid product was filtered off and recrystallised from n-butanol to give 1-(p-chlorobenzamido)pyridinium chloride (209 parts, 97% yeild), melting point 241° C.

Workup

  1. filtrationThe solid product was filtered off
  2. customrecrystallised from n-butanol

Sources & evidence

ORD record
ord-4ac86e48557b4936ba9b579fe9468f7b
Source dataset
uspto-grants-1977_03
Patent number
US04013669

Reaction notes

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