4,6-Dichloro-2-methylquinoline → 6-Chloro-2-methyl-1,2,3,4-tetrahydroquinoline

HRID 597530Notes

Reaction equation

HRID 597530 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([Cl:12])[CH:10]=2)[N:5]=[C:4]([CH3:13])[CH:3]=1>[Rh]>[Cl:12][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][CH:8]=1)[NH:5][CH:4]([CH3:13])[CH2:3][CH2:2]2

Participants

3

Reactant 1

HCID 123225774,6-Dichloro-2-methylquinoline

Product 1

HCID 131253006-Chloro-2-methyl-1,2,3,4-tetrahydroquinoline

Reagents, catalysts & solvents 1

HCID 23948RhodiumCatalyst

Procedure

4,6-Dichloroquinaldine was reduced with rhodium on carbon to give 6-chloro-2-methyltetrahydroquinoline.

Sources & evidence

ORD record
ord-a8c25d6d59f2435888994e3307fb4195
Source dataset
uspto-grants-1977_03
Patent number
US04014877

Reaction notes

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