HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 597583Generated: October 25, 2026
Hydrazine hydrate (1:1) → 3,5-Diphenyl-4-methylpyrazoline
https://huagongshe.com/reaction/597583
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | alpha-Methylchalcone | HCID 99812 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3,5-Diphenyl-4-methylpyrazoline | HCID 70639070 | 88.9% |
Reaction Steps
Isolated α-methylchalcone, 1.5 g (85% pure product by gas liquid chromatography) (0.00578 mole) is reacted with 0.55 g (0.008 mole) of 75% hydrazine hydrate in 7.5 ml of methanol and 1 ml of water under N2 at reflux (68° C) for 1 hour. Gas liquid chromatography shows the α-methylchalcone had reacted to form 3,5-diphenyl-4-methylpyrazoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04014896 |
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| Source dataset | uspto-grants-1977_03 |
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| ORD ID | ord-71f587f73c1b4fbb99d15de02474861f |
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| Source note | uspto-grants-1977_03 |
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