HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 3,5-Diphenyl-4-methoxypyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | alpha-Methylchalcone | HCID 99812 | — |
| Reactant | 2,3-dihydro-1H-pyrazole | HCID 4156003 | — |
| Reactant | 3,5-Diphenyl-4-methoxypyrazoline | HCID 68117438 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 3,5-Diphenyl-4-methoxypyrazole | HCID 12498521 | — |
Reaction Steps
Following the procedure of Example 1 but substituting α-methoxychalcone for α-methylchalcone, and reacting the same with hydrazine hydrate, there is prepared 3,5-diphenyl-4-methoxypyrazoline. The so-formed pyrazoline is then reacted with Pd/C at reflux to obtain 3,5-diphenyl-4-methoxypyrazole in good yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04014896 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-f790a37f3f694e10be2af2feedb1248f |
| Source note | uspto-grants-1977_03 |