Isopropylamine → HCID 86734590, compound

HRID 597645Notes

Reaction equation

HRID 597645 reaction equation
C(O[C:6]([NH:8][CH:9]=[CH:10][C:11]1[CH:21]=[CH:20][C:14]([O:15][CH2:16][CH:17]2[O:19][CH2:18]2)=[CH:13][CH:12]=1)=[O:7])CCC.[CH:22]([NH2:25])([CH3:24])[CH3:23]>C(O)(C)C>[CH2:14]([O:15][C:9]([N:8]=[C:6]=[O:7])=[CH:10][C:11]1[CH:12]=[CH:13][C:14]([O:15][CH2:16][CH:17]([OH:19])[CH2:18][NH:25][CH:22]([CH3:24])[CH3:23])=[CH:20][CH:21]=1)[CH2:13][CH2:12][CH3:11]

Participants

4

Reactant 2

HCID 6363IsopropylamineHCID 53853551HCID 53853551, compound

Product 1

HCID 86734590HCID 86734590, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Analogously to the description in Example 2, 3.93 g (0.0135 mol) of 1-[p-(2-n-butoxycarbonylaminovinyl)-phenoxy]-2,3-epoxy-propane, on reaction with 1.22 ml (0.0142 mol) of isopropylamine in 50 ml of isopropanol, yield 1-[p-(2-n-butoxy-carbonylaminovinyl)-phenoxy]-2-hydroxy-3-isopropylaminopropane of melting point 125°-126°C (from acetone-ether).

Sources & evidence

ORD record
ord-16831830438547f28dd7c6a8b3a27efa
Source dataset
uspto-grants-1977_03
Patent number
US04014920

Reaction notes

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