Hydrazine → 6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione

Participants

Reaction Conditions

Reaction Steps

To a mixture containing 10.0 g (62.28 mmol) of 6-chloro-3-methyluracil in 200 ml of ethanol was added 13.70 ml (436.50 mmol) of hydrazine. The mixture was heated to 75° C. under a nitrogen atmosphere overnight. The solids were filtered, washed with ethanol and dried to afford 9.70 g (99.74%) of product as a pale yellow solid.

Provenance & Evidence