反应详情

To a solution containing 0.2 g (0.73 mmol) of 1-(2,4-dimethylbenzyl)-3-methyl-5-nitropyridin-2(1H)-one in 50 ml of methanol was added 0.017 g (0.073 mmol) of platinum (IV) oxide (Adam's catalyst). The flask was fitted with a balloon of hydrogen and allowed to stir for 1 h. The reaction was filtered through GF/F paper and the filtrate concentrated under reduced pressure to afford 0.11 g (62%) of product.

1. filtrationThe reaction was filtered through GF/F paper
2. concentrationthe filtrate concentrated under reduced pressure