4-Chlorobenzyl cyanide → HCID 73050958, compound

HRID 59843Notes

Reaction equation

HRID 59843 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=O)=[CH:15][CH:14]=3)=[CH:11][CH:10]=[N:9]2)=[CH:4][CH:3]=1.[Cl:22][C:23]1[CH:28]=[CH:27][C:26]([CH2:29]C#N)=[CH:25][CH:24]=1>>[Cl:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]2[O:21][N:19]=[C:16]3[CH:15]=[CH:14][C:13]([C:12]4[N:8]([C:5]5[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=5)[N:9]=[CH:10][CH:11]=4)=[CH:18][C:17]=23)=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 2415824-Chlorobenzyl cyanideHCID 900325491-(4-chloro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole2×

Product 1

HCID 73050958HCID 73050958, compound

Procedure

The title compound, light green solid (111 mg, 82%), MS (ISP) m/z=406.2 [(M+H)+], mp 222° C., was prepared in accordance with the general method of example 1 from 1-(4-chloro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole (intermediate H) (100 mg, 353 μmol) and commercially available 2-(4-chloro-phenyl)-acetonitrile.

Sources & evidence

ORD record
ord-a072745296e4448e8daf6fc2855c6c8d
Source dataset
uspto-grants-2016_09
Patent number
US09440962B2

Reaction notes

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