HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Chloro-6-(trifluoromethyl)quinoxaline → (5-Methyl-2-trifluoromethyl-phenyl)-[(R)-3-(6-trifluoromethyl-quinoxalin-2-ylamino)-pyrrolidin-1-yl]-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Chloro-6-(trifluoromethyl)quinoxaline | HCID 3547342 | — |
| Edukt | ((R)-3-Amino-pyrrolidin-1-yl)-(5-methyl-2-trifluoromethyl-phenyl)-methanone | HCID 57748952 | — |
| Produkt | (5-Methyl-2-trifluoromethyl-phenyl)-[(R)-3-(6-trifluoromethyl-quinoxalin-2-ylamino)-pyrrolidin-1-yl]-methanone | HCID 57748860 | — |
Reaktionsschritte
In analogy to the procedure described for example 200, the title compound was prepared from 2-chloro-6-trifluoromethyl-quinoxaline and ((R)-3-amino-pyrrolidin-1-yl)-(5-methyl-2-trifluoromethyl-phenyl)-methanone (intermediate 13). (M+H+) 469.2.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07897627B2 |
| Quelldatensatz | uspto-grants-2011_03 |
| ORD ID | ord-cfd0afe295f948b0be04cc070eb2aac4 |
| Quellennotiz | uspto-grants-2011_03 |