HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-((1,1-Dimethylethoxy)carbonyl)-4-(trifluoromethyl)-L-phenylalanine → HCID 178434254, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-((1,1-Dimethylethoxy)carbonyl)-4-(trifluoromethyl)-L-phenylalanine | HCID 7021025 | — |
| Reactant | Edc hobt | HCID 86583742 | — |
| Reactant | HCID 178434255 | HCID 178434255 | — |
| Product | HCID 178434254 | HCID 178434254 | — |
Reaction Steps
This intermediate was prepared by EDC-HOBt coupling of 5-(3-methyl-1H-indazol-5-yl)oxazol-2-amine with (S)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)propanoic acid (purchased from Peptech (CAS No. 114873-07-3)) using a standard procedure such as described in Bioorg. Med. Chem. 14(2), 418-425; 2006) which is hereby incorporated by reference in its entirety as if specifically set forth herein.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07897619B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-45aea12d31a34f1c96e3f322e8b69387 |
| Source note | uspto-grants-2011_03 |