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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 598831Generated: October 25, 2026

N-((1,1-Dimethylethoxy)carbonyl)-4-(trifluoromethyl)-L-phenylalanine → HCID 178434254, compound

https://huagongshe.com/reaction/598831

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-((1,1-Dimethylethoxy)carbonyl)-4-(trifluoromethyl)-L-phenylalanineHCID 7021025—
ReactantEdc hobtHCID 86583742—
ReactantHCID 178434255HCID 178434255—
ProductHCID 178434254HCID 178434254—

Reaction Steps

This intermediate was prepared by EDC-HOBt coupling of 5-(3-methyl-1H-indazol-5-yl)oxazol-2-amine with (S)-2-(tert-butoxycarbonylamino)-3-(4-(trifluoromethyl)phenyl)propanoic acid (purchased from Peptech (CAS No. 114873-07-3)) using a standard procedure such as described in Bioorg. Med. Chem. 14(2), 418-425; 2006) which is hereby incorporated by reference in its entirety as if specifically set forth herein.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07897619B2
Source datasetuspto-grants-2011_03
ORD IDord-45aea12d31a34f1c96e3f322e8b69387
Source noteuspto-grants-2011_03