Ammonia → HCID 67152113, compound

Participants

Reaction Steps

Prepared from (4s)-1-azatricyclo[3.3.1.13,7]dec-4-ylamine hydrochloride and thieno[2,3-c]pyridine-5-carboxylic acid (Tetrahedron Lett. 1999, 40, 7935) according to methods A and C; yield 82 mg, 0.21 mmol (59%): 1H NMR (300 MHz, methanol-d4) δ 2.03 (d, J=14 Hz, 2H), 2.25 (s, 1H), 2.39 (d, J=14 Hz, 2H), 2.55 (s, 2H), 3.61 (s, 2H), 3.72 (s, 4H), 4.54 (s, 1H), 7.91 (d, J=5 Hz, 1H), 8.62 (d, J=5 Hz, 1H), 9.01 (s, 1H), 9.57 (s, 1H); MS (DCI/NH3) m/z 314 (M+H)+; Anal. C17H19N3OS.2HCl.1.0H2O: C, H, N.

Provenance & Evidence