Hydrochloric Acid → HCID 67063119, compound

Participants

Reaction Steps

To a solution of N2,N4-dimethyl-5-nitropyrimidine-2,4-diamine (4 g, 21.8 mmol) in EtOH was added 10% Pd/C (0.5 g) and 1 N aq HCl solution (10 mL, 10 mmol). The mixture was hydrogenated (30 psi) for 2 h. The reaction mixture was filtered and the filtrate was concentrated to give N2,N4-dimethylpyrimidine-2,4,5-triamine HCl (4 g, 97% yield). 1H NMR (400 MHz, CD3OD): δ 9.00 (s, 1 H), 3.45 (s, 3 H), 3.35 (s, 3 H).

Provenance & Evidence