Hydrochloric Acid → 1-[(3-Pyridin-3-yl-8-azabicyclo[3.2.1]oct-8-yl)carbonyl]-1,2,3,4-tetrahydroquinoline hydrochloride

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Reaction Steps

0.146 g of 1-[(3-pyridin-3-yl-8-azabicyclo[3.2.1]oct-8-yl)carbonyl]-1,2,3,4-tetrahydroquinoline is dissolved in 6 ml of dichloromethane and 4.2 ml of a 4N solution of hydrochloric acid in dioxane are added. After evaporation, the residue is taken up in ethyl acetate. The precipitate is filtered off and then dried under vacuum. 0.122 g of 1-[(3-pyridin-3-yl-8-azabicyclo[3.2.1]oct-8-yl)carbonyl]-1,2,3,4-tetrahydroquinoline hydrochloride is obtained.

Provenance & Evidence