Hydrochloric Acid → HCID 24961601, compound

HRID 599355Notes

Reaction equation

HRID 599355 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]2[CH:13]3[N:14]([C:15]([N:17]4[C:26]5[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=5)[CH2:20][CH2:19][CH2:18]4)=[O:16])[CH:10]([CH2:11][CH2:12]3)[CH2:9][CH2:8]2)[CH:2]=1.[ClH:27]>CCOCC>[ClH:27].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]2[CH:13]3[N:14]([C:15]([N:17]4[C:26]5[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=5)[CH2:20][CH2:19][CH2:18]4)=[O:16])[CH:10]([CH2:11][CH2:12]3)[CH2:9][CH2:8]2)[CH:2]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 249616021-[(4-Pyridin-3-yl-8-azabicyclo[3.2.1]oct-8-yl)carbonyl]-1,2,3,4-tetrahydroquinoline

Product 1

HCID 24961601HCID 24961601, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

0.04 g of 1-[(4-pyridin-3-yl-8-azabicyclo[3.2.1]oct-8-yl)carbonyl]-1,2,3,4-tetrahydroquinoline is dissolved in 1.15 ml of a 0.2N solution of hydrochloric acid in ether. After evaporation, the residue is taken up in ethyl acetate. The precipitate is filtered off and then dried under vacuum. 0.004 g of 1-[(4-pyridin-3-yl-8-azabicyclo[3.2.1]oct-8-yl)carbonyl]-1,2,3,4-tetrahydroquinoline hydrochloride is obtained.

Workup

  1. customAfter evaporation
  2. filtrationThe precipitate is filtered off
  3. customdried under vacuum

Sources & evidence

ORD record
ord-8c8db3af723041d1ad5b1084b11f89ee
Source dataset
uspto-grants-2011_03
Patent number
US07897773B2

Reaction notes

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