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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 599514Generated: October 30, 2026

Hydrochloric Acid → HCID 59848750, compound

https://huagongshe.com/reaction/599514

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 59848688HCID 59848688—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 59848750HCID 59848750—

Reaction Steps

t-Butyl (2-{[4-(3-cyano-5-{[2-(methylamino)ethoxy]methyl}pyridin-2-yl)benzoyl]amino}phenyl)carbamate (465 mg, 0.93 mmol, prepared as described in Method 30), 1,4-dioxane (3.5 ml) and a 4M solution of hydrogen chloride in 1,4-dioxane (3.5 ml) were stirred at ambient temperature for 4 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07897778B2
Source datasetuspto-grants-2011_03
ORD IDord-7e7c7f99e5874971a09a2b0803834123
Source noteuspto-grants-2011_03