HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Ethyl([1,4']bipiperidinyl-4-yloxy)-acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Tert-butyl([1,4']bipiperidinyl-4-yloxy)-acetate | HCID 86261192 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl([1,4']bipiperidinyl-4-yloxy)-acetate | HCID 57807779 | — |
Reaction Steps
A solution of 100 mg (0.33 mmol) tert.butyl ([1,4′]bipiperidinyl-4-yloxy)-acetate in 1 mL EtOH was combined with 2 mL ethanolic HCl with heating, the mixture was refluxed for a further 2 h and left overnight at RT. The precipitate formed was suction filtered and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07897603B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-a8327505435d4236ad192f47c69843fe |
| Source note | uspto-grants-2011_03 |