反应详情

A solution of 100 mg (0.33 mmol) tert.butyl ([1,4′]bipiperidinyl-4-yloxy)-acetate in 1 mL EtOH was combined with 2 mL ethanolic HCl with heating, the mixture was refluxed for a further 2 h and left overnight at RT. The precipitate formed was suction filtered and dried.

1. temperaturewith heating
2. temperaturethe mixture was refluxed for a further 2 h
3. customThe precipitate formed
4. filtrationfiltered
5. customdried