反应详情

Dissolving 3,4,5-trimethoxyl benzyl bromide (16.05 g, 61.47 mmol) in toluene (150 ml) in a three-necked bottle (250 ml), adding triphenylphosphine (16.12 g, 61.47 mmol) and dissolving immediately, heating to reflux for 1 hour, white solid being separated, cooling to room temperature, suction filtering, and washing the filter cake with toluene (30 ml). After vacuum drying, 3,4,5-trimethoxyl benzyl triphenylphosphine bromide (27.81 g of white powder solid) was isolated, yield: 86.44%.

1. dissolutiondissolving immediately
2. temperatureheating
3. temperatureto reflux for 1 hour
4. customwhite solid being separated
5. filtrationsuction filtering
6. washwashing the filter cake with toluene (30 ml)
7. customAfter vacuum drying