反应详情

Dimethyl 1,4-dipropylnaphthalene-2,3-dicarboxylate (0.295 g, 0.898 mmol) was added to a 5 ml THF solution of LiAlH4 (0.075 g, 1.98 mmol) at 0° C. After stirring at room temperature for an hour, water was added to effect hydrolysis. The mixture was treated with 2N H2SO4 followed by extraction with diethyl ether. The extract was washed with brine and dried over anhydrous magnesium sulfate. The extract was concentrated under reduced pressure. The title compound (0.219 g) was obtained as a white solid. The isolation yield was 90%.

1. extractionfollowed by extraction with diethyl ether
2. washThe extract was washed with brine
3. dry with materialdried over anhydrous magnesium sulfate
4. concentrationThe extract was concentrated under reduced pressure