Piperidine → HCID 67272489, compound

Participants

Reaction Steps

(6-Piperidin-1-yl-5,6,7,8-tetrahydro-naphthalen-2-yl)-(2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone is prepared from 1-(6-bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-piperidine and (S)-(+)-1-(2-pyrrolidinylmethyl)-pyrrolidine in a manner substantially analogous to Procedure A. (See herein Example 1). Starting material, (6-bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-piperidine, was prepared from 6-bromo-2-tetralone and piperidine in a manner substantially analogous to Preparation 1. Mass Spectrum (ES+) 396.

Provenance & Evidence