Pyrrolidine → HCID 44216396, compound

Participants

Reaction Steps

(2-Pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-(6-pyrrolidin-1-yl-5,6,7,8-tetrahydro-naphthalen-2-yl)-methanone is prepared from 1-(6-bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-pyrrolidine and (S)-(+)-1-(2-pyrrolidinylmethyl)-pyrrolidine in a manner substantially analogous to Procedure A. (See herein Example 1). Starting material, (6-bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-pyrrolidine, was prepared from 6-bromo-2-tetralone and pyrrolidine in a manner substantially analogous to Preparation 1. Mass Spectrum (APCI) 382 (M++1).

Provenance & Evidence