反应详情

(6-Benzylamino-5,6,7,8-tetrahydro-naphthalen-2-yl)-(2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone is prepared from benzyl-(6-bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine and (S)-(+)-1-(2-pyrrolidinylmethyl)-pyrrolidine in a manner substantially analogous to Procedure A. (See herein Example 1). Starting material, benzyl-(6-bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine, can be prepared from 6-bromo-2-tetralone and benzylamine in a manner substantially analogous to Preparation 1. Mass spectrum (APCI) 418 (M++1).