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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 600246Generated: October 29, 2026

Butylamine → HCID 67273095, compound

https://huagongshe.com/reaction/600246

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButylamineHCID 8007—
Reactant(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidineHCID 853152—
Reactant6-Bromo-2-tetraloneHCID 2733553—
ReactantHCID 63625845HCID 63625845—
ProductHCID 67273095HCID 67273095—

Reaction Steps

(6-Butylamino-5,6,7,8-tetrahydro-naphthalen-2-yl)-(2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone is prepared from (6-bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-butyl-amine and (S)-(+)-1-(2-pyrrolidinylmethyl)-pyrrolidine in a manner substantially analogous to Procedure A. (See herein Example 1). Starting material, (6-bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-butyl-amine, was prepared from 6-bromo-2-tetralone and n-butylamine in a manner substantially analogous to Preparation 1. Mass spectrum (APCI) 384 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902191B2
Source datasetuspto-grants-2011_03
ORD IDord-e920fe347c4f450892e43e6bb2fced5e
Source noteuspto-grants-2011_03