Hydrochloric Acid → (1R,2R)-1-Amino-2-phenylcyclopropane-1-carboxylic acid hydrochloride

Participants

Reaction Steps

A mixture of (1R,2R)-methyl 1-amino-2-phenylcyclopropanecarboxylate (14 mg), water (4 mL) and hydrochloric acid (37% w/v, 6 mL) was heated under reflux for 6 h. The mixture was evaporated to dryness, triturated with diethyl ether and the solid collected and dried to give the subtitle compound (14 mg) as a colourless solid.

Provenance & Evidence