HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (6-Methylimidazo[1,2-a]pyridin-2-yl)phenylmethanone hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | (6-Methylimidazo[1,2-a]pyridin-2-yl)phenylmethanone | HCID 24768843 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | (6-Methylimidazo[1,2-a]pyridin-2-yl)phenylmethanone hydrochloride | HCID 24768842 | — |
Reaction Steps
120 mg of (6-methylimidazo[1,2-a]pyridin-2-yl)phenylmethanone are taken up in 2 mL of ethanol and the solution is treated with 1.5 mL of a 4N solution of hydrogen chloride in dioxane and then with 2 mL of diethyl ether. The crystals obtained are filtered off and washed with diethyl ether, and then dried. 77 mg of (6-methylimidazo[1,2-a]pyridin-2-yl)phenylmethanone hydrochloride (1:1) are obtained in the form of a beige-colored solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07902219B2 |
| Source dataset | uspto-grants-2011_03 |
| ORD ID | ord-445964f76f124d37b0ef99fba4cea7ba |
| Source note | uspto-grants-2011_03 |