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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 600623Generated: October 29, 2026

Sodium Hydroxide → HCID 67273847, compound

https://huagongshe.com/reaction/600623

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantSodium DithioniteHCID 24489—
ReactantHCID 67273481HCID 67273481—
SolventEthanolHCID 702—
ProductHCID 67273847HCID 67273847—

Reaction Steps

0.42 g of 2-benzoyl-6-nitroimidazo[1,2-a]pyridine in 20 mL of boiling ethanol is treated with 10 mL of 0.5 N sodium hydroxide solution and 2.77 g of sodium dithionite. After 10 minutes at 80° C., the reaction medium is cooled, filtered and concentrated to dryness to give the crude (6-aminoimidazo[1,2-a]pyridin-2-yl)(phenyl)methanone, which is used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902219B2
Source datasetuspto-grants-2011_03
ORD IDord-598a927f9d684d0b937799d8892e411e
Source noteuspto-grants-2011_03