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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 600790Generated: October 30, 2026

8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-one → HCID 11964288, compound

https://huagongshe.com/reaction/600790

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-oneHCID 11955840—
ReactantHCID 11964287HCID 11964287—
ProductHCID 11964288HCID 11964288—

Reaction Steps

The title compound was prepared using the procedure as described in Example 2, substituting the product of Example 12C for the product of Example 1I. 1H NMR (DMSO-d6) δ 8.64 (s, 1H), 7.55 (d, 1H, J=7.7 Hz), 7.05 (t, 1H, J=7.6 Hz), 6.77 (d, 1H, J=7.1 Hz), 6.41 (s, 1H), 4.76 (d, 1H, J=4.1 Hz), 3.90 (m, 1H), 2.72-2.94 (m, 3H), 1.63-2.05 (m, 18H); MS (ESI+) m/z 365 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902236B2
Source datasetuspto-grants-2011_03
ORD IDord-0ee6a6a36fbc4e04ade63a853329fbbd
Source noteuspto-grants-2011_03