HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 601044Generated: October 30, 2026
HCID 58976101, compound → HCID 58976675, compound
https://huagongshe.com/reaction/601044
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 58976101 | HCID 58976101 | — |
| Reactant | HCID 62250707 | HCID 62250707 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 58976675 | HCID 58976675 | 66.5% |
Reaction Steps
A mixture of N-cyano-N′-(4-morpholinopheny)-O-phenylisourea (0.10 g, 0.31 mmol) and [2-(4-Methyl-piperazin-1-yl)-pyrimidin-4-yl]-hydrazine (0.08 g, 0.34 mmol) in N-methylpyrrolidinone (3 mL) was heated in the microwave apparatus at 220° C. for 5 min. Purification by semi-preparative HPLC provided the title compound (0.09 g, 2% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07902239B2 |
|---|
| Source dataset | uspto-grants-2011_03 |
|---|
| ORD ID | ord-732849bf0e5d4c148c293a02c5035efd |
|---|
| Source note | uspto-grants-2011_03 |
|---|