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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 601044Generated: October 30, 2026

HCID 58976101, compound → HCID 58976675, compound

https://huagongshe.com/reaction/601044

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 58976101HCID 58976101—
ReactantHCID 62250707HCID 62250707—
SolventN-methyl-2-pyrrolidoneHCID 13387—
ProductHCID 58976675HCID 5897667566.5%

Reaction Conditions

Temperature220 °C

Reaction Steps

A mixture of N-cyano-N′-(4-morpholinopheny)-O-phenylisourea (0.10 g, 0.31 mmol) and [2-(4-Methyl-piperazin-1-yl)-pyrimidin-4-yl]-hydrazine (0.08 g, 0.34 mmol) in N-methylpyrrolidinone (3 mL) was heated in the microwave apparatus at 220° C. for 5 min. Purification by semi-preparative HPLC provided the title compound (0.09 g, 2% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902239B2
Source datasetuspto-grants-2011_03
ORD IDord-732849bf0e5d4c148c293a02c5035efd
Source noteuspto-grants-2011_03