Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 601116Generated: October 29, 2026

Ethyl 2-[(2-ethylbutyl)amino]nicotinate → 1-Benzyl-7-methyl-2H-pyrido[2,3-d][1,3]oxazine-2,4(1H)-dione

https://huagongshe.com/reaction/601116

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-[(2-ethylbutyl)amino]nicotinateHCID 67064133—
ReactantHCID 86592109HCID 86592109—
Product1-Benzyl-7-methyl-2H-pyrido[2,3-d][1,3]oxazine-2,4(1H)-dioneHCID 49758043—

Reaction Steps

The title compound was prepared according to the procedure of Example 3B substituting the product of Example 62A for the product of Example 3A (0.150 g, 50%). 1H NMR (300 MHz, CDCl3) δ 2.66 (s, 3H), 5.47 (s, 2H), 7.10 (d, J=8.09 Hz, 1H), 7.31 (m, 3H), 7.55 (dd, J=7.54, 1.65 Hz, 2H), 8.26 (d, J=8.09 Hz, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902203B2
Source datasetuspto-grants-2011_03
ORD IDord-4b358f14345a4690a9f0ace4a1e2b720
Source noteuspto-grants-2011_03