Trifluoroacetic acid → HCID 43670440, compound

HRID 601625Notes

Reaction equation

HRID 601625 reaction equation
C(O)(C(F)(F)F)=O.C(OC(=O)[NH:14][CH2:15][CH2:16][C:17]1[O:21][N:20]=[C:19]([CH2:22][CH2:23][CH3:24])[N:18]=1)(C)(C)C>C(Cl)Cl>[CH2:22]([C:19]1[N:18]=[C:17]([CH2:16][CH2:15][NH2:14])[O:21][N:20]=1)[CH2:23][CH3:24]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 57466817[2-(3-Propyl-[1,2,4]oxadiazol-5-yl)-ethyl]-carbamic acid tert-butyl ester

Product 1

HCID 43670440HCID 43670440, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

TFA (6 ml) is added to a stirred solution of [2-(3-propyl-[1,2,4]oxadiazol-5-yl)-ethyl]-carbamic acid tert-butyl ester (0.67 g, 2.62 mmol) in DCM (10 ml). After 1 hor the solvents are removed to afford the titled compound.

Workup

  1. customAfter 1 hor the solvents are removed

Sources & evidence

ORD record
ord-fb30a434a59248d786ebc0459fc86b02
Source dataset
uspto-grants-2011_03
Patent number
US07902375B2

Reaction notes

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