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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 601650Generated: October 29, 2026

Dimethylformamide → HCID 11349506, compound

https://huagongshe.com/reaction/601650

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantSodium hydrideHCID 24758—
ReactantHCID 11439986HCID 11439986—
CatalystMethyl iodideHCID 6328—
ProductHCID 11349506HCID 11349506—

Reaction Steps

At room temperature, 3 mg of 60% of sodium hydride was added to 1 ml solution of dimethylformamide with 10 mg of 1-(2-fluoropyridine-3-yl)-4-(1-oxo-2-methylcarbonyloxy-indane-5-yl)-5-methyl-1H-[1,2,3]triazole, obtained in Example 45. After stirring 30 min at room temperature, 5 drops of methyl iodide was added and the mixture was further stirred for 1 hour at room temperature.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902369B2
Source datasetuspto-grants-2011_03
ORD IDord-90217c9637f14ba696263e31c0ffd11f
Source noteuspto-grants-2011_03