Lithium hydroxide, monohydrate → HCID 44125121, compound

Participants

Reaction Steps

The title compound was synthesized from methyl 4-(4-isopropylbenzyl)-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carboxylate and lithium hydroxide monohydrate according to General Procedure 7. Silica gel was added, the solvent stripped off and the silica gel-imbedded material was purified by flash chromatography (0-80% EtOAc/Heptane) to give 4-(4-isopropylbenzyl)-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carboxylic acid (33) as a light yellow solid.

Provenance & Evidence