反应详情

(E)-Methyl 4-(3-(furan-2-yl)benzylidene)-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carboxylate (0.066 g, 0.207 mmol) was dissolved in ethyl acetate (5 mL). Then palladium on carbon (5%) was added and the reaction placed under a hydrogen atmosphere using a balloon, stirred at room temperature for 5 h, then filtered through celite. The filtrate was concentrated and purified by column chromatography (Isco CombiFlash) eluting with a gradient of 0-25% EtOAc/heptane affording the title compound. 0.028 g.

1. filtrationfiltered through celite
2. concentrationThe filtrate was concentrated
3. custompurified by column chromatography (Isco CombiFlash)
4. washeluting with a gradient of 0-25% EtOAc/heptane affording the title compound