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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 601922Generated: October 30, 2026

Lithium Hydroxide → 6-(3,4-Difluorophenyl)-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carboxylic acid

https://huagongshe.com/reaction/601922

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantEthyl 6-(3,4-difluorophenyl)-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carboxylateHCID 59180205—
SolventWaterHCID 962—
Product6-(3,4-Difluorophenyl)-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carboxylic acidHCID 59180056—

Reaction Steps

The title compound was synthesized from ethyl 6-(3,4-difluorophenyl)-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carboxylate and lithium hydroxide in water according to General Procedure 7.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07902252B2
Source datasetuspto-grants-2011_03
ORD IDord-c365739afb024a83ad1540b257f3bb0b
Source noteuspto-grants-2011_03