cis-Crotyl Bromide → HCID 59180186, compound

HRID 601944Notes

Reaction equation

HRID 601944 reaction equation
[CH3:1][Si:2]([CH3:14])([CH3:13])[C:3]#[C:4][CH2:5][O:6][CH:7]1[CH2:12][CH2:11][CH2:10][CH2:9][O:8]1.Br[CH2:16]/[CH:17]=[CH:18]\[CH3:19]>>[CH3:14][Si:2]([CH3:13])([CH3:1])[C:3]#[C:4][CH:5]([O:6][CH:7]1[CH2:12][CH2:11][CH2:10][CH2:9][O:8]1)[CH2:16]/[CH:17]=[CH:18]\[CH3:19]

Participants

3

Reactant 2

HCID 5354843cis-Crotyl BromideHCID 107037813-TETRAHYDROPYRANYLOXY-1-TRIMETHYLSILYL-1-PROPYNE

Product 1

HCID 59180186HCID 59180186, compound

Procedure

Reaction of trimethyl(3-(tetrahydro-2H-pyran-2-yloxy)prop-1-ynyl)silane (0.157 g, 0.74 mmol) and (Z)-1-bromobut-2-ene (0.12 g, 0.89 mmol) according to General Procedure 11.A provided (Z)-trimethyl(3-(tetrahydro-2H-pyran-2-yloxy)hept-5-en-1-ynyl)silane. The (Z)-1-bromobut-2-ene starting material was synthesized in two steps according to General Procedures 11.F and 11.G.

Sources & evidence

ORD record
ord-eedfeddc061b47158b280c2acc2c6cf7
Source dataset
uspto-grants-2011_03
Patent number
US07902252B2

Reaction notes

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