Benzene → HCID 59180203, compound

HRID 601947Notes

Reaction equation

HRID 601947 reaction equation
[CH3:1][Si:2]([CH3:14])([CH3:13])[C:3]#[C:4][CH2:5][O:6][CH:7]1[CH2:12][CH2:11][CH2:10][CH2:9][O:8]1.[CH:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH3:14][Si:2]([CH3:13])([CH3:1])[C:3]#[C:4][CH:5]([O:6][CH:7]1[CH2:12][CH2:11][CH2:10][CH2:9][O:8]1)[CH2:9]/[CH:10]=[CH:11]\[CH2:12][CH2:7][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 241BenzeneHCID 107037813-TETRAHYDROPYRANYLOXY-1-TRIMETHYLSILYL-1-PROPYNE

Product 1

HCID 59180203HCID 59180203, compound

Procedure

Reaction of trimethyl(3-(tetrahydro-2H-pyran-2-yloxy)prop-1-ynyl)silane (4.6 g, 21.6 mmol 4.6 g, 21.6 mmol) and (z)-5-bromo-pent-3-enyl)-benzene, (4.1 g, 18 mmol)) according to General Procedure 11.A provided the title compound. The material was used in the next step without purification.

Sources & evidence

ORD record
ord-7051f465bf504a7ea2e82cc3ff77213f
Source dataset
uspto-grants-2011_03
Patent number
US07902252B2

Reaction notes

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