反应详情

To 100 ml of toluene were added 13.0 g of 4-(2-propynyloxy)-3,5-dimethoxybenzoic acid, 9.5 g of thionyl chloride and 50 mg of DMF and the mixture obtained was heated under reflux for 3 hours. Then, the reaction mixture was concentrated. The solid obtained was washed with hexane to obtain 12.0 g of 4-(2-propynyloxy)-3,5-dimethoxybenzoyl chloride represented by the formula:

1. customthe mixture obtained
2. temperaturewas heated
3. temperatureunder reflux for 3 hours
4. concentrationThen, the reaction mixture was concentrated
5. customThe solid obtained
6. washwas washed with hexane